Chitosan-aprotinin coated liposomes for oral peptide delivery: Development, characterisation and in vivo evaluationWERLE, Martin; TAKEUCHI, Hirofumi.International journal of pharmaceutics (Print). 2009, Vol 370, Num 1-2, pp 26-32, issn 0378-5173, 7 p.Article

Evaluation of mucoadhesiveness of polymers by BIACORE method and mucin-particle methodTHONGBORISUTE, Jringjai; TAKEUCHI, Hirofumi.International journal of pharmaceutics. 2008, Vol 354, Num 1-2, pp 204-209, issn 0378-5173, 6 p.Article

In vivo evaluation of riboflavin-containing microballoons for floating controlled drug delivery system in healthy human volunteersSATO, Yasunori; KAWASHIMA, Yoshiaki; TAKEUCHI, Hirofumi et al.Journal of controlled release. 2003, Vol 93, Num 1, pp 39-47, issn 0168-3659, 9 p.Article

Evaluation of circulation profiles of liposomes coated with hydrophilic polymers having different molecular weights in ratsTAKEUCHI, Hirofumi; KOJIMA, Hiroyuki; YAMAMOTO, Hiromitsu et al.Journal of controlled release. 2001, Vol 75, Num 1-2, pp 83-91, issn 0168-3659Article

Novel pectin-based nanoparticles prepared from nanoemulsion templates for improving in vitro dissolution and in vivo absorption of poorly water-soluble drugBURAPAPADH, Kanokporn; TAKEUCHI, Hirofumi; SRIAMORNSAK, Pornsak et al.European journal of pharmaceutics and biopharmaceutics. 2012, Vol 82, Num 2, pp 250-261, issn 0939-6411, 12 p.Article

A novel application of α-glucosyl hesperidin for nanoparticle formation of active pharmaceutical ingredients by dry grindingTOZUKA, Yuichi; IMONO, Masaaki; UCHIYAMA, Hiromasa et al.European journal of pharmaceutics and biopharmaceutics. 2011, Vol 79, Num 3, pp 559-565, issn 0939-6411, 7 p.Article

Fluorescence investigation of a specific structure formed by aggregation of transglycosylated stevias: Solubilizing effect of poorly water-soluble drugsUCHIYAMA, Hiromasa; TOZUKA, Yuichi; ASAMOTO, Fusatoshi et al.European journal of pharmaceutical sciences. 2011, Vol 43, Num 1-2, pp 71-77, issn 0928-0987, 7 p.Article

In vitro and in vivo evaluation of WGA-carbopol modified liposomes as carriers for oral peptide deliveryMAKHLOF, Abdallah; FUJIMOTO, Shiho; TOZUKA, Yuichi et al.European journal of pharmaceutics and biopharmaceutics. 2011, Vol 77, Num 2, pp 216-224, issn 0939-6411, 9 p.Article

Improvement of dissolution and absorption properties of poorly water-soluble drug by preparing spray-dried powders with α-glucosyl hesperidinUCHIYAMA, Hiromasa; TOZUKA, Yuichi; IMONO, Masaaki et al.International journal of pharmaceutics (Print). 2010, Vol 392, Num 1-2, pp 101-106, issn 0378-5173, 6 p.Article

Release profile of insulin entrapped on mesoporous materials by freeze-thaw methodTOZUKA, Yuichi; SUGIYAMA, Eri; TAKEUCHI, Hirofumi et al.International journal of pharmaceutics (Print). 2010, Vol 386, Num 1-2, pp 172-177, issn 0378-5173, 6 p.Article

PH-Sensitive nanospheres for colon-specific drug delivery in experimentally induced colitis rat modelMAKHLOF, Abdallah; TOZUKA, Yuichi; TAKEUCHI, Hirofumi et al.European journal of pharmaceutics and biopharmaceutics. 2009, Vol 72, Num 1, pp 1-8, issn 0939-6411, 8 p.Article

Molecularly imprinted polymer-assisted refolding of lysozymeHARUKI, Mitsuru; KONNAI, Yoshihiro; SHIMADA, Ayumi et al.Biotechnology progress. 2007, Vol 23, Num 5, pp 1254-1257, issn 8756-7938, 4 p.Article

In vitro and in vivo evaluation of riboflavin-containing microballoons for a floating controlled drug delivery system in healthy humansSATO, Yasunori; KAWASHIMA, Yoshiaki; TAKEUCHI, Hirofumi et al.International journal of pharmaceutics. 2004, Vol 275, Num 1-2, pp 97-107, issn 0378-5173, 11 p.Article

pH-sensitive microsphere delivery increases oral bioavailability of calcitoninLAMPRECHT, Alf; YAMAMOTO, Hiromitsu; TAKEUCHI, Hirofumi et al.Journal of controlled release. 2004, Vol 98, Num 1, pp 1-9, issn 0168-3659, 9 p.Article

Physicochemical properties to determine the buoyancy of hollow microspheres (microballoons) prepared by the emulsion solvent diffusion methodSATO, Yasunori; KAWASHIMA, Yoshiaki; TAKEUCHI, Hirofumi et al.European journal of pharmaceutics and biopharmaceutics. 2003, Vol 55, Num 3, pp 297-304, issn 0939-6411, 8 p.Article

Determination of optimum processing temperature for transformation of glyceryl monostearateYAJIMA, Toshio; ITAI, Shigeru; TAKEUCHI, Hirofumi et al.Chemical and pharmaceutical bulletin. 2002, Vol 50, Num 11, pp 1430-1433, issn 0009-2363, 4 p.Article

Passive targeting of doxorubicin with polymer coated liposomes in tumor bearing ratsTAKEUCHI, Hirofumi; KOJIMA, Hiroyuki; YAMAMOTO, Hiromitsu et al.Biological & pharmaceutical bulletin. 2001, Vol 24, Num 7, pp 795-799, issn 0918-6158Article

Nanoparticles of glycol chitosan and its thiolated derivative significantly improved the pulmonary delivery of calcitoninMAKHLOF, Abdallah; WERLE, Martin; TOZUKA, Yuichi et al.International journal of pharmaceutics (Print). 2010, Vol 397, Num 1-2, pp 92-95, issn 0378-5173, 4 p.Article

Development and In Vitro Characterization of Liposomes Coated with Thiolated Poly(Acrylic Acid) for Oral Drug DeliveryWERLE, Martin; HIRONAKA, Kohei; TAKEUCHI, Hirofumi et al.Drug development and industrial pharmacy. 2009, Vol 35, Num 2, pp 209-215, issn 0363-9045, 7 p.Article

Cyclodextrins as stabilizers for the preparation of drug nanocrystals by the emulsion solvent diffusion methodMAKHLOF, Abdallah; MIYAZAKI, Yuta; TOZUKA, Yuichi et al.International journal of pharmaceutics. 2008, Vol 357, Num 1-2, pp 280-285, issn 0378-5173, 6 p.Article

Die wall pressure measurement for evaluation of compaction property of pharmaceutical materialsTAKEUCHI, Hirofumi; NAGIRA, Shinsuke; YAMAMOTO, Hiromitsu et al.International journal of pharmaceutics. 2004, Vol 274, Num 1-2, pp 131-138, issn 0378-5173, 8 p.Article

Design and evaluation of novel pH-sensitive chitosan nanoparticles for oral insulin deliveryMAKHLOF, Abdallah; TOZUKA, Yuichi; TAKEUCHI, Hirofumi et al.European journal of pharmaceutical sciences. 2011, Vol 42, Num 5, pp 445-451, issn 0928-0987, 7 p.Article

A novel method for modifying AFM probe to investigate the interaction between biomaterial polymers (Chitosan-coated PLGA) and mucin filmDONGXING LI; YAMAMOTO, Hiromitsu; TAKEUCHI, Hirofumi et al.European journal of pharmaceutics and biopharmaceutics. 2010, Vol 75, Num 2, pp 277-283, issn 0939-6411, 7 p.Article

Transglycosylated stevia and hesperidin as pharmaceutical excipients: Dramatic improvement in drug dissolution and bioavailabilityUCHIYAMA, Hiromasa; TOZUKA, Yuichi; IMONO, Masaaki et al.European journal of pharmaceutics and biopharmaceutics. 2010, Vol 76, Num 2, pp 238-244, issn 0939-6411, 7 p.Article

Effect of surface properties of liposomes coated with a modified polyvinyl alcohol (PVA-R) on the interaction with macrophage cellsNAKANO, Koji; TOZUKA, Yuichi; TAKEUCHI, Hirofumi et al.International journal of pharmaceutics. 2008, Vol 354, Num 1-2, pp 174-179, issn 0378-5173, 6 p.Article